Installation of GPMAW version 10.00.

Released on November 1st, 2014.

The following installation files will all install the same version of GPMAW on your system, but due to variations in Windows and access rights of users, a number of different install programs are presented.

Upgrade of GPMAW.
Download for 32-bit Windows. (file name ‘GPupdate32.exe’).
Download for 64-bit Windows. (file name ‘GPupdate64.exe’).
This will only install the executable file, help file and documentation. This is the file with the smallest footprint and is recommended for upgrading..
Note: This is not a complete system and is only useful for upgrading an existing system. If you have problems with the upgrade on a 64-bit system, please contact Lighthouse data.

All install systems mentioned below are full installs and need the license file (gpmaw.lcs) in order to complete installation.
To perform an installation you should download to a temporary directory, copy your license file (‘gpmaw.lcs’) to the same directory, and then activate (double-click) the .exe file.

32-bit installer (file name ‘GPsetup32.exe’). Click for download.
Standard installer for 32-bit Windows. You need to include ‘gpmaw.lcs’ file in the same directory as the setup file in order to get a working system.

64-bit installer (file name ‘GPsetup64.exe’). Click for download.
Standard installer for 32-bit Windows. You need to include ‘gpmaw.lcs’ file in the same directory as the setup file in order to get a working system.

’Classic’ installer The old installers ‘setup.exe’ and ‘SetupNoDb.exe’ are no longer supplied as you are likely to run into problems on newer versions of Windows.

If you want to have a look at the full manual, you can find it here.

New features in version 10.0.

A large number of small changes have been made that are too numerous to detail. A number of smaller errors have also been corrected without comment.

• Multimodifications improved
• msms search: modifiable cleavages
• msms search: automatic file numbering; more options (persistent)
• msms search: protein mass in table, save sequence as FastA file
• SS disulfide bridges removed from peptide window. Disulfide calculations reworked.
• Peptide window re-worked
• Mass search reworked. New report function.
• Residue surrounds (peptide cleavage menu)
• The toolbar of the main, peptide and sequence window now has an option on the Setup | Display page: Persistent Menus - when checked menu information is saved in the Registry, when unchecked the menus positions are not persistent. On some machines checking this options leads to an error when closing the program.
• The report in mass search did not always report correct coverage with more than two peptides in a given position.
• A new 'fly-by' highlight can be selected in the highlight residues menu (last option).
• Isotopic mass distribution did not include mass of extra atoms (e.g. Fe, Cu etc.). Monoisotopic mass, but not isotopes, are now included.
• If Cys is modified and the SS button changed to SH, isotopic distibution was 1 Da off.
• An error leading to displaying wrong sequence when searching with a sequence offset corrected.
• MALDI de novo option - determining sequences from singly charged (MALDI) ms/ms spectra
• Display error in peptide list when displaying more than 1000 peptides has been fixed
• View FastA sequences properties (called from ms/ms or separately from File | Retrieve)
• Error in terminals of ms/ms fragmentation when called from peptide window
• SS disulfide bridges improved in peptide window
• ClustalW improved and font issue resolved.